Why Kidneys Start Getting Damaged: Understanding the Causes

Lav Tripathi
3 min readOct 7, 2023

The kidneys are vital organs that play a crucial role in maintaining the body’s overall health and balance.

They are responsible for filtering waste products and excess fluids from the blood, regulating blood pressure, and helping in the production of red blood cells.

However, kidneys can become damaged over time due to various factors.

In this article, we will explore the reasons why kidneys start getting damaged.

1. High Blood Pressure

One of the leading causes of kidney damage is high blood pressure, also known as hypertension.

When blood pressure remains consistently high, it can put excessive strain on the small blood vessels in the kidneys, impairing their ability to filter blood effectively.

Over time, this can lead to kidney damage and, in severe cases, kidney failure.

2. Diabetes

Diabetes, particularly type 2 diabetes, is another major contributor to kidney damage.

High levels of glucose in the blood can damage the tiny blood vessels in the kidneys, as well as the filtering units called nephrons.

This condition, known as diabetic nephropathy, can gradually lead to chronic kidney disease (CKD) if not managed properly.

3. Glomerulonephritis

Glomerulonephritis refers to inflammation of the glomeruli, which are the tiny filtering units within the kidneys.

This condition can result from various factors, including infections, autoimmune diseases, and certain medications.

When the glomeruli are damaged, the kidneys lose their ability to filter waste and excess fluid properly, leading to kidney damage.

4. Urinary Tract Infections (UTIs)

Recurrent or severe urinary tract infections can pose a risk to kidney health.

If bacteria from a UTI travel up to the kidneys, they can cause inflammation and infection.

This can result in scarring of the kidney tissue and potential long-term damage.

5. Kidney Stones

The formation of kidney stones is a common occurrence that can lead to kidney damage if not addressed.

Kidney stones are hard deposits of minerals and salts that can block the urinary tract, causing pain and potential damage to the kidneys.

Chronic or recurrent kidney stone formation can increase the risk of kidney damage over time.

6. Polycystic Kidney Disease (PKD)

Polycystic kidney disease is a genetic condition characterized by the growth of fluid-filled cysts in the kidneys.

As these cysts enlarge, they can damage kidney tissue and impair their function.

PKD is a progressive condition and can lead to kidney failure if left untreated.

7. Medications and Toxins

Certain medications and toxins, when consumed or exposed to in high amounts, can damage the kidneys.

Non-steroidal anti-inflammatory drugs (NSAIDs), some antibiotics, and certain pain relievers can have adverse effects on kidney function.

Additionally, exposure to environmental toxins like heavy metals and solvents can also harm the kidneys.

8. Autoimmune Diseases

Autoimmune diseases, such as lupus and vasculitis, can cause inflammation in various parts of the body, including the kidneys.

This chronic inflammation can lead to kidney damage over time.

Early diagnosis and treatment of autoimmune conditions are crucial to prevent kidney complications.

9. Aging

As we age, our kidneys naturally undergo some changes, such as a decrease in the number of nephrons and a decrease in blood flow.

These age-related changes can reduce kidney function and make them more susceptible to damage.

It is essential for older adults to maintain a healthy lifestyle and manage underlying health conditions to support kidney health.

Conclusion

Kidney damage can result from various factors, including high blood pressure, diabetes, infections, kidney stones, genetic conditions, medications, and autoimmune diseases.

Recognizing the causes of kidney damage is essential for preventing and managing kidney-related problems.

Maintaining a healthy lifestyle, managing underlying health conditions, and seeking early medical intervention when necessary are crucial steps in preserving kidney health and preventing long-term damage.

Read Also

How Long Does it Take to Die from Kidney Failure Without Dialysis

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Lav Tripathi

Writer| blogger| travel enthusiast. Talks about #Astronomy #Cosmology #Stock trading #Health Creator of www.lavtripathi.com